Clinical efficacy of topical propranolol cream on strawberry hemangiomas in proliferative phase
10.3760/cma.j.issn.1671-0290.2016.04.009
- VernacularTitle:2％普萘洛尔乳膏治疗婴幼儿增殖期草莓状血管瘤的临床效果
- Author:
Xingcun ZHANG
;
Yunchuan YANG
;
Yuanyuan WANG
;
Yang GAO
;
Junbo ZHANG
;
Hailin WANG
;
Yuangang LU
- Publication Type:Journal Article
- Keywords:
Propranolol cream;
Infant;
Strawberry hemangioma
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2016;22(4):218-220
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy and safety of topical 2％ propranolol cream for strawberry hemangiomas in proliferative phase.Methods Sixty infants with strawberry hemangiomas in proliferative phase were included in this study.There were 18 males and 42 females aged 30 days to 12 months.The lesions were located in head and neck (n=30),trunk (n=19) and extremities (n =11).All the infants received the 2％ propranolol cream treatment three times per day.The infants were required a regular return visit every month.The changes of tumor size,texture and color were monitored and recorded.The adverse effects after medication were observed and managed accordingly.The short-term results were evaluated using a 4-grade system.Results All the infants were followed up for 12 months.Among 60 infants,the Ⅰ,Ⅱ,Ⅲ and Ⅳ grade curative effects were 2,17,33 and 8 cases,respectively.All the infants had no drug adverse reaction.Conclusions The effect of topical 2％ propranolol cream for strawberry hemangiomas in proliferative phase is reliable,with little side effects.It will be popularized in clinical application.
