A new hemostatic clip with sutures for suspension in endoscopic submucosal dissection
10.3760/cma.j.issn.1007-5232.2016.05.012
- VernacularTitle:内镜黏膜下剥离术中新型带线缝合夹悬吊法的实验研究
- Author:
Jun FANG
;
Jing XIE
;
Yaping LIU
;
Xingang SHI
;
Dong WANG
;
Zhaoshen LI
- Publication Type:Journal Article
- Keywords:
Suture techniques;
Endoscopic submucosal dissection;
Suspension method;
In vitro porcine stomach
- From:
Chinese Journal of Digestive Endoscopy
2016;33(5):321-325
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the safety and effectiveness of a new hemostatic clip with sutures for ESD suspension method in animal models.Methods A total of 20 porcine stomachs were randomly divided into the experimental group (n=10) and the control group (n=10).ESD was done respectively in antrum greater curvature and antrum back wall of porcine stomach in vitro.All procedures were completed by the same endoscopist and nurse.The incidence of perforation,mucosa diameter,total operation time (T),dissection time (T1),the average number of submucosal injection,and one-time complete dissection rate were compared between two groups.Results Procedures were done successfully in antrum of 40 poccine in vitro and all mucosa were dissected completely in one procedure.No perforation occurred.Compared with the control group,the mucosa diameter difference was not statistically significant (P =0.368).The total operating time [(34.70± 1.06) min VS (37.1 0± 2.23) min,P =0.009],dissection time [(31.40± 2.00) min VS (34.80± 2.20) min,P=0.817] and the average number of submucosal injection[(7.60± 1.00) VS (10.60± 1.00),P＜0.001] in antral greater curvature ESD of the experimental group were significantly less than those of the control group.As for the antrum back wall,the mucosa diameter difference was not statistically significant.The total operation time [(37.00± 1.25) min VS (39.60± 1.65) min,P＜0.001],dissection time[(34.50± 1.35) min VS (37.00± 1.25) min,P＜0.001],the average number of submucosal injection [(7.60± 1.27) VS (11.40± 1.00),P＜0.001] were also significantly less than those of the control.Conclusion The new hemostatic clip with sutures for suspension can significantly shorten the operation time,reduce the number of submucosal injections and the difficulty in ESD.
