Follow-up of endoscopic submucosal dissection for early esophageal cancer
10.3760/cma.j.issn.1007-5232.2016.05.009
- VernacularTitle:内镜黏膜下剥离术治疗食管早癌的随访及疗效分析
- Author:
Fei XIAO
;
Shuping YANG
;
Lianzhen YU
;
Ruihua SHI
;
Tingsheng LING
;
Guoxin ZHANG
- Publication Type:Journal Article
- Keywords:
Follow-up studies;
Endoscopic submucosal dissection;
Esophageal neoplasms
- From:
Chinese Journal of Digestive Endoscopy
2016;33(5):308-311
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the intermediate and long-term efficacy of endoscopic submucosal dissection (ESD) for early esophageal cancer(EEC).Methods A total of 56 patients with EEC underwent ESD at Jiangsu Province People's Hospital between April 2010 and June 2015.Among the 56 cases,there were 39 cases of intramucosal cancer,17 cases of submucosal cancer.Intravascular cancer embolus was found in 2 patients.The en bloc and complete resection rates,the residual,local tumor recurrence and new occurrence rates of EEC after ESD were evaluated.The average follow-up time was 24.4 months,ranging from 1 to 62 months.Results The en bloc and complete resection rates were 92.9%(52) and 87.5% (49),respectively.Four patients were treated by additional esophagectomy.The cases of residual lesions,local tumor recurrence,new occurrence and second primary extra-esophageal cancer (gastric cancer) was 1 (1.8%),2 (3.6%),2 (3.6%) and 2 (3.6%),respectively.No additional surgical operations were performed in the 7 patients or no recurrence was found,and there was no death during the follow-up period.Conclusion ESD has the advantage of high complete resection rate,low residual and local tumor recurrence rate in treatment of EEC,and the intermediate and long-term outcomes are satisfactory.