A survival analysis of primary duodenal carcinoma after radical resection

VernacularTitle:原发性十二指肠癌根治性切除患者的预后分析
Author: Lijun WANG ; Kun WANG ; Quan BAO ; Yi SUN ; Hongwei WANG ; Kemin JIN ; Baocai XING
Publication Type:Journal Article
Keywords: Duodenal neoplasms; Lymphatic metastasis; Prognosis
From: Chinese Journal of General Surgery 2016;31(7):565-568
CountryChina
Language:Chinese
Abstract: Objective To investigate survival for primary duodenal carcinoma patients after radical resection and identify risk factors associated with overall survival.Methods Data of 51 patients with primary duodenal carcinomas who underwent radical resection between December 2003 and December 2012 at Beijing Cancer Hospital were included.Survival analysis was drawn by Kaplan-Meier method,univariate and multivariate analyses were performed to identify variables associated with survival after resection by COX regression model.Results The median overall survival time was 67 months,and the median disease-free time was 40 months,1-,2-and 3-year overall survival rates were 88％,84％ and 67％,respectively.Multivariate analysis revealed that regional lymph-node positive (P =0.032) and CA199 ＞ 37 U/ml (P =0.037) were independent risk factors of patients' overall survival.Conclusions Radical resection improves survival for primary duodenal carcinoma patients.Regional lymph-node positive and CA199 ＞37 U/ml were the most important risk factors of patients'overall survival.