Comparison of value predicting prognosis between ENETS and AJCC TNM staging system in gastric neuroendocrine carcinoma patients

VernacularTitle:不同TNM分期标准在胃神经内分泌癌患者预后评估中的价值
Author: Jianming WEI ; Tong LIU
Publication Type:Journal Article
Keywords: Neuroendocrine tumors; Neoplasm staging; Prognosis
From: Chinese Journal of General Surgery 2016;31(6):449-452
CountryChina
Language:Chinese
Abstract: Objective To compare the value for predicting prognosis between ENETS and AJCC TNM staging system in G-NEC patients.Methods Clinical data of 28 G-NEC cases from January 2005 to September 2015 in Tianjin Medical University General Hospital were analyzed and follow-up data were staged by he ENETS and AJCC TNM staging system.The survival curves were drawn using Kaplan-Meier method.Univariate analysis was performed by Log-rank test.Results Evaluated by ENETS TNM staging system on these 28 G-NEC patients,5 cases (18％) were classified at stage Ⅱ,20 cases (71％) were at stage Ⅲ,3 cases (11％) at stage Ⅳ,and significant difference in survival time was found between the three stages (P ＜ 0.05).By the AJCC TNM staging system,1 case (4％) was classified at stage Ⅱ,24 cases (86％) were at stage Ⅲ,and 3 cases (11％) at stage Ⅳ,and significant difference in survival time was found between three stages.Conclusions AJCC TNM staging system is more valuable for predicting prognosis of G-NEC,while the ENETS TNM staging system is more accurate in evaluating G-NEC biologic behavior.