Effect of dexmedetomidine on quality of recovery from anesthesia in patients undergoing modified electroconvulsive therapy with propofol anesthesia
10.3760/cma.j.issn.0254-1416.2016.04.013
- VernacularTitle:右美托咪定对丙泊酚麻醉下无抽搐电休克治疗患者麻醉恢复质量的影响
- Author:
Xiang LI
;
Na GUO
;
Nan CHENG
;
Shaoli ZHOU
;
Ziqing HEI
- Publication Type:Journal Article
- Keywords:
Dexmedetomidine;
Propofol;
Electroconvulsive therapy;
Anesthesia recovery period
- From:
Chinese Journal of Anesthesiology
2016;36(4):430-432
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of dexmedetomidine on the quality of recovery from anesthesia in the patients undergoing modified electroconvulsive therapy (MECT) with propofol anesthesia.Methods One hundred and ten patients of both sexes,aged 18-50 yr,weighing 45-80 kg,of American Society of Anesthesiologists physical status Ⅰ or Ⅱ,scheduled for elective MECT with general anesthesia,were randomly assigned into 2 groups (n =55 each) using a random number table:control group (group C) and dexmedetomidine group (group D).Dexmedetomidine was infused intravenously in a dose of 0.5 μg/kg (in normal saline 10 ml) over 10 min in group D,while normal saline 10 ml was infused intravenously over 10 min in group C.Propofol 1.5 mg/kg and succinylcholine 0.5 mg/kg were injected intravenously,and MECT was performed in the two groups.The emergence time was recorded.The development of cardiovascular events,nausea and vomiting,respiratory depression,headache,somnolence and agitation during recovery from anesthesia was recorded.Results Compared with group C,the incidence of nausea and vomiting,headache and agitation during recovery from anesthesia was significantly decreased (P＜0.05),and no significant changes were found in the emergence time,and incidence of hypertension,tachycardia,respiratory depression and somnolence during recovery from anesthesia in group D (P＞ 0.05).Conclusion Dexmedetomidine (intravenously infused in a dose of 0.5 μg/kg over 10 min before anesthesia) can raise the quality of recovery from anesthesia in the patients undergoing MECT with propofol anesthesia.
