Changes and maintenance measures of liver physiological function in donor of brain death

VernacularTitle:脑死亡供体肝脏生理功能改变及维护措施的探讨
Author: Wei WANG ; Qifa YE ; Qi XIAO ; Zhongzhong LIU ; Yanfeng WANG
Publication Type:Journal Article
Keywords: Brain death; Process of brain death; Liver physiological function; Liver quality; Maintenance measure
From: Chinese Journal of Hepatobiliary Surgery 2016;22(7):493-496
CountryChina
Language:Chinese
Abstract: The quality and function of the donor liver is one of the main factors which influence the success and prognosis of liver transplantation.At present,the major source of donor liver for transplantation is Donor of Brain Death (DBD) all over the world,which has unstable circulation.When the brain death occurs,a series of serious physiological function changes will be induced within a few minutes and affect the hemodynamics and homeostasis of the body,which will greatly influence the liver quality and function,and consequently the success and prognosis of liver transplantation,finally leading to the loss of potential donor organs.Therefore,it is necessary to identify the physiological function changes induced by the process of brain death and its injury to liver and take immediate proper protective measures,which can effectively reduce the organ injury,improve liver function and enhance the organ utilization and liver transplantation success.In this paper,the changes and maintenance measures of liver physiological function in DBD will be reviewed.