Research advances in the pathogenesis of radiation-induced myocardial damage
10.3760/cma.j.issn.1004-4221.2016.06.025
- VernacularTitle:放射性心脏损伤发病机制研究进展
- Author:
Yajing WU
;
Jun WANG
;
Yi WANG
- Publication Type:Journal Article
- Keywords:
Radiation induced cardiac injury;
Pathogenesis;
Thoracic neoplasms/radiotherapy
- From:
Chinese Journal of Radiation Oncology
2016;25(6):657-660
- CountryChina
- Language:Chinese
-
Abstract:
The Medline and CNKI databases were searched with the key words of radiation-induced myocardial damage,damage pathway,pathogenesis,and intervention,and 37 articles were obtained.The pathogenesis of radiation-induced myocardial damage may be related to various mechanisms such as oxidative stress,transforming growth factor-β,renin-angiotensin system,mast cells,and endothelial dysfunction.The pathogenesis of radiation-induced myocardial damage is a complex process involving various mechanisms,and currently,there are ongoing studies on the cellular and molecular mechanisms involved in its pathogenesis and interventions.