The progresses of mechanistic studies of the effect of NF-κB on radiation damage
10.3760/cma.j.issn.0254-5098.2016.07.016
- VernacularTitle:NF-κB在放射性损伤中的表达改变及作用机制的研究进展
- Author:
Meng ZHANG
;
Juying ZHOU
- Publication Type:Journal Article
- Keywords:
NF-κB;
Radiation damage;
NF-κB inhibitor
- From:
Chinese Journal of Radiological Medicine and Protection
2016;36(7):553-557
- CountryChina
- Language:Chinese
-
Abstract:
The number of people needed to accept radiotherapy is increasing with the higher incidence of tumor,and the continuous development of radiation therapy technology has extended the longterm survival of patients.Avoiding the occurrence of radiation damage is particularly important.Since NF-κB plays an important role in gene transcription and regulation of radiation damage,this article introduced the structure,activation and function of NF-κB,reviewed the findings of NF-κB alterations in radiation injuries of brain and lung,and sketched the studies of NF-κB inhibitor.
