Nasal continuous positive airway pressure in pediatric patients with respiratory failure after liver transplantation
10.3760/cma.j.issn.0254-1785.2016.02.002
- VernacularTitle:经鼻持续正压通气治疗婴幼儿肝移植术后呼吸功能衰竭
- Author:
Yan SUN
;
Lixin YU
- Publication Type:Journal Article
- Keywords:
Infant patients;
Liver transplantation;
Nasal continuous positive airway pressure;
Respiratory failure
- From:
Chinese Journal of Organ Transplantation
2016;37(2):70-75
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of nasal continuous positive airway pressure (nCPAP) in pediatric patients with respiratory failure after liver transplantation.Method A prospective? randomized controlled clinical trial was conducted during June 1st 2013 to June lst2015 in 71 pediatric patients with respiratory failure after liver transplantation.A total of 66 patients completed the trial and 5 patients quitted.Conventional oxygen therapy group included 35 cases and nCPAP group included 31 cases.The vital sign,blood-gas analysis,intra-abdominal pressure and prognosis were compared between the two groups.Result After nCPAP treatment,the heart rate,respiratory rate,and PCO2 decreased at 4 and 24 h (P＜0.05),oxygenation index was improved at 24 and 48 h (P＜0.05),and intra-abdominal pressure decreased at 48 h (P＜0.05).nCPAP showed better outcome than conventional oxygen therapy (P＜0.05).The incidence of refractory atelectasis,intra-abdominal hypertension,and epilepsy was higher in treatment failure population.Conclusion nCPAP is more suitable for pediatric patients with respiratory failure after liver transplantation,especially for those accompanied with intra-abdominal hypertension.
