A Case of Trichilemmal Carcinoma.
10.5021/ad.1998.10.3.175
- Author:
Gwang Bum AHN
;
Seung Ho CHANG
;
Tae Young YOON
- Publication Type:Case Report
- Keywords:
Trichilemmal carcinoma;
High molecular weight cytokeratin
- MeSH:
Aged;
Aged, 80 and over;
Cytoplasm;
Female;
Hair Follicle;
Humans;
Immunohistochemistry;
Keratins;
Molecular Weight;
Skin
- From:Annals of Dermatology
1998;10(3):175-178
- CountryRepublic of Korea
- Language:English
-
Abstract:
Trichilemmal carcinoma is a rare tumor that is located predominantly on sun-exposed skin of the elderly. It is thought to be related to the external root sheath of the hair follicle and the malignant counterpart of a trichilemmoma. We report a case of trichilemmal carcinoma in a 88-year-old woman who had a 10 year history of a single, dark brown tumor on the right preauricular region. In her past medical history, it had been excised twice at a private clinic without a histopathological evaluation and recurred 2 years later. Histopathological findings showed atypical clear cells resembling those of the outer root sheath. Tumor cells showed PAS-positive cytoplasm. Immunohistochemistry revealed positive high molecular weight cytokeratin expression. To our knowledge, this is the second case of trichilemmal carcinoma in the Korean literature. (Ann Dermatol 100) 175178, 1998).
