Added diagnostic value of CT attenuation correction for spinal lesions in SPECT bone imaging
10.3760/cma.j.issn.2095-2848.2016.03.011
- VernacularTitle:CT衰减校正对脊柱病灶SPECT显像的增益价值
- Author:
Haojun YU
;
Yiqiu ZHANG
;
Beilei LI
;
Liang CAI
;
Shuguang CHEN
;
Hongcheng SHI
- Publication Type:Journal Article
- Keywords:
Spinal diseases;
Diagnosis,differential;
Tomography,emission-computed,single-photon;
Tomogarphy,X-ray computed;
MDP
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2016;36(3):250-254
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the added value of CTAC for improving image quality and diagnostic efficiency of bone imaging in SPECT/CT.Methods Seventy-five patients (47 males,28 females,(56.6± 12.8) years) with abnormal uptake in planar whole-body bone scintigraphy underwent SPECT/CTfor differentiation of malignant from benign spinal lesions.NAC and CTAC SPECT images were classified based on 5-point scale (5:excellent,4:good,3:adequate,2:suboptimal,1:inadequate).The diagnostic confidence for both NAC and CTAC SPECT images were classified based on 4-point scale (4:definite,3:certain,2:equivocal,1:uninterpretable).The pathological results after surgery were used as gold standard to evaluate the added diagnostic value of CTAC for spinal lesions.Wilcoxon-signed rank sum test was used for data analysis.Results CTAC improved the image quality in 37.3％ (28/75) of patients,and downgraded in 2.7％ (2/75) of patients.The remaining 45 patients were unchanged (60.0％,45/75).SPECT with CTAC could significantly improve the image quality (z=-4.747,P＜0.001),but the overall diagnostic confidence was not increased (z=-1.000,P＞0.05).Conclusion CTAC can improve the image quality of spinal SPECT,especially useful in imaging with poorer quality,but it has no significant incremental value in diagnostic confidence.
