Neonatal Lupus Erythematosus.
10.5021/ad.1998.10.3.185
- Author:
Ho Pyo LEE
;
Hye Nam LEE
;
Dong HOUH
;
Dae Gyoo BYUN
;
Seung Cheol BAEK
- Publication Type:Case Report
- Keywords:
Neonatal lupus erythematosus;
Autoantibodies
- MeSH:
Antibodies, Antinuclear;
Autoantibodies;
Female;
Follow-Up Studies;
Heart Block;
Humans;
Infant;
Lupus Erythematosus, Cutaneous
- From:Annals of Dermatology
1998;10(3):185-189
- CountryRepublic of Korea
- Language:English
-
Abstract:
Neonatal lupus erytematosus is a distinct subset of lupus erythematosus. It is characterized by cutaneous findings exhibiting the morphology of subacute cutaneous lupus erythematosus, congenital heart block, and anti-Ro/SSA and/or anti-La/SSB autoantibodies which result from the transplacental passage of maternal autoantibodies. We report a case of a 12-week-old female infant who presented with characteristic clinical and histopathological features of cutaneous neonatal lupus erythematosus but without evidence of congenital heart block. Initial serological studies reveled the presence of anti-La/SSB anti-bodies and antinuclear antibodies. 5 months later, follow-up serology was negative in accordance with a clinical remission.
