Research progress of nuclear medicine imaging in detection of vulnerable atherosclerotic plaques
10.3760/cma.j.issn.2095-2848.2016.04.022
- VernacularTitle:核医学显像在动脉粥样硬化易损斑块中的研究进展
- Author:
Hui TAN
;
Dengfeng CHENG
;
Hongcheng SHI
- Publication Type:Journal Article
- Keywords:
Plaque,atherosclerotic;
Nuclear medicine;
Diagnosis;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2016;36(4):367-370
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis is a vascular inflammatory disease.Vulnerable atherosclerotic plaques mainly lead to severe cardiovascular and cerebrovascular diseases,such as myocardial infarction and stroke.The research on the early diagnosis of vulnerable plaques becomes currently urgent.As a noninvasive molecular modality,the nuclear medicine imaging (with specific radiolabeled probes) has been used for the detection of unstable plaques,and for the evaluation of therapeutic effect of anti-atherosclerotic drugs.Nuclear imaging techniques for detecting metabolic activity,inflammation,hypoxia,angiogenesis,apoptosis,and microcalcification in unstable plaques are summarized in this review.
