Research progress of T-2 toxin induced effects on pregnant mice and generation mice
10.3760/cma.j.issn.2095-4255.2016.07.019
- VernacularTitle:T-2毒素对孕鼠及子代小鼠影响的研究进展
- Author:
Tiantian LI
;
Haijuan REN
;
Yanhong CAO
- Publication Type:Journal Article
- Keywords:
T-2 toxin;
Pregnant mice;
Generation mice
- From:
Chinese Journal of Endemiology
2016;35(7):540-542
- CountryChina
- Language:Chinese
-
Abstract:
T-2 toxin is a secondary fungal metabolite that belongs to the trichothecene mycotoxin family,it is the most toxic in class A trichothecene mycotoxin.T-2 toxin can induce apoptosis in cells bearing high proliferating activity.The mycotoxin readily passes the placenta and is distributed to embryo tissues,which results in fetal brain damage,bone malformation,thymic atrophy and even death.This article reviewed the effects of T-2 toxin on immune system,blood system and cell toxicities in pregnant mice and generation mice.
