Significance of HP detection in patients of chronic urticaria
10.3969/j.issn.1000-484X.2016.07.026
- VernacularTitle:慢性荨麻疹患者幽门螺杆菌检测的意义
- Author:
Chunmiao WANG
;
Weishi WU
;
Jinhong ZHU
;
Maohua ZHOU
;
Weisha WANG
- Publication Type:Journal Article
- Keywords:
Chronic urticaria;
Helicobacter pylori;
Colloidal gold method
- From:
Chinese Journal of Immunology
2016;32(7):1050-1052
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the correlation between chronic urticaria and Helicobacter pylori infection,and to explore the significance of HP detection in the diagnosis and treatment of chronic urticaria. Methods: Totally 420 cases of chronic urticaria,who were treated in outpatient department from April 2014 to July 2015,and 450 cases of healthy physical people were selected randomly as healthy control group in the same period,then the serum HP unease antibody was detected by colloidal gold method,the positive rate of two groups patients with HP was analysed. Meanwhile 162 chronic urticaria patients with positive HP were divided into experimental group with 88 cases and control group with 74 cases. The patients in the control group were treated with conventional treatment,while the experimental group were treated with triple therapy based on the treatment of control group,and the clinical efficacy of different ther-apeutic methods was analysed in the chronic urticaria patients with positive HP. Results: The positive rate of HP in chronic urticaria group was 38. 6%, and the positive rate of HP in healthy control group was 14. 4%, the difference was statistically significant ( P<0. 05). The effective rate of clinical efficacy in the experimental group was significantly higher than the control group(P<0. 05). Con-clusion:There is close correlation between chronic urticaria and HP infection,HP detection has important clinical significance for the diagnosis and treatment of chronic urticaria.
