Clinical features and follow-up of 35 children with post-infectious bronchiolitis obliterans

VernacularTitle:儿童感染后闭塞性细支气管炎35例临床特点及随访研究
Author: Yanshan ZHOU ; Qubei LI
Publication Type:Journal Article
Keywords: bronchiolitis obliterans; infection; glucocorticoids
From: Journal of Clinical Pediatrics 2016;34(7):526-528
CountryChina
Language:Chinese
Abstract: Objective To analyze the clinical characteristics, treatment, and prognosis of post-infectious bronchiolitis obliterans (PIBO) in children. Methods Clinical data from 35 children diagnosed with PIBO were retrospectively analyzed from April 2010 to June 2015 . The children were divided into different groups according to the length of glucocorticoid use, and the prognosis were compared. Results Thirty-ifve children all presented cough and wheezing. There were 12 cases in the group of less than one year of glucocorticoid treatment, 8 cases in the group of 1-2 years of glucocorticoid treatment, and 6 cases in the group of great than or equal to 2 years of glucocorticoid treatment. There was no signiifcant difference in the prognosis among the groups (P>?0 . 05 ). Conclusions The overall prognosis is poor in children with PIBO, even if the symptoms are improved. Glucocorticoid is helpful to remiss the symptoms of cough and wheezing, but prolonged use have no signiifcant effect on the prognosis.