Current status and prospects of the immune pathogenesis and treatment of IgA vasculitis
10.3760/cma.j.issn.2095-428X.2016.09.001
- VernacularTitle:IgA血管炎的免疫机制和治疗现状及展望
- Author:
Sirui YANG
;
Deying LIU
;
Jinghua WANG
;
Jinxiang LIU
;
Congcong LIU
- Publication Type:Journal Article
- Keywords:
Immunoglobulin A vasculitis;
Pathogenesis;
Therapy;
Glucocorticoid
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(9):641-645
- CountryChina
- Language:Chinese
-
Abstract:
IgA vasculitis (IgAV) is a common systemic small-sized vessel vasculitis.It's characterized by non-thrombocytopenic palpable purpura,arthralgia/arthritis,bowel angina,and nephritis,but some details of etiology and pathogenesis is not very clear.The disease course is usually benign and self-limited,however,it is necessary to discuss the therapy of severe or chronic cases,especially there is not enough evidence-based basis for using key drugs to IgAV.Excellent clinical trails is expected to establish scientific system of prediction and evaluation of disease course,which will be helpful to individualize treatment of IgAV.
