Current mocular diagnostic technologies in drug related gene detection and its quality control system
10.3760/cma.j.issn.1009-9158.2016.07.015
- VernacularTitle:药物相关基因的分子检测技术及其质量监测的发展现状
- Author:
Yun BAO
;
Yanqun XIAO
;
Hualiang WANG
- Publication Type:Journal Article
- Keywords:
Pharmocogenomics;
Genetic testing;
Quality control;
Reference standards
- From:
Chinese Journal of Laboratory Medicine
2016;39(7):532-535
- CountryChina
- Language:Chinese
-
Abstract:
Personalized medicine has revolutionized patients ′care, and results in a personalized drug choice and dosage, through integration of pharmacology , drug information and individual ′s genetics information.The genetic testing for genes involved in drug metabolisms and targets become more and more important.However, the variety of the tests as well as the complexity of the technology brought great challenges in laboratory managements and quality assurance for individual clinical laboratory .This article briefly described the development status of pharmacogenomics and focused mainly on the routine quality assurance principle for four different techniques adopted by related genetic testing , and then presented recent research progression of related reference materials in genetic testing .Finally, the author prospects briefly the future development aspect of the quality control system .