Progress of diagnosis and treatment of asparaginase associated pancreatitis in children
10.3760/cma.j.issn.2095-428X.2016.15.006
- VernacularTitle:门冬酰胺酶相关儿童急性胰腺炎诊治研究进展
- Author:
Wei SHI
- Publication Type:Journal Article
- Keywords:
Asparaginase;
Asparaginase associated pancreatitis;
Leukemia;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(15):1140-1143
- CountryChina
- Language:Chinese
-
Abstract:
Asparaginase(ASP) is an important drug in the treatment of childhood acute lymphoblastic leukemia and non-Hodgkin lymphoma.Asparaginase associated pancreatitis (AAP) is the main treatment-adverse events of asparaginase.After reviewing the recent foreign literatures about AAP and the Chinese expert about polyethylene glycol conjugated asparaginase (PEG-ASP) in the treatment of acute lymphoblastic leukemia and malignant lymphoma with asparaginase,conclude and analysis the data about childhood AAP and show the epidemiology,clinical features,early diagnosis and effective treatment of children with AAP.Make clinical compare of L-asparaginase and PEG-ASP.Based on the full grasp of the relevant data,analyzing,introducing and integrating,this may be helpful to the diagnosis and treatment of childhood AAP.
