Effects of oral calcium and active vitamin D on bone mineral density and balance function in senile osteoporosis patients
10.3760/cma.j.issn.0254-9026.2016.06.016
- VernacularTitle:骨矿化物治疗对老年骨质疏松患者平衡能力的影响及效果分析
- Author:
Li ZHANG
;
Xiuli AN
;
Lina LIANG
- Publication Type:Journal Article
- Keywords:
Osteoporosis;
Bone density
- From:
Chinese Journal of Geriatrics
2016;35(6):629-633
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of oral calcium and active vitamin D on bone mineral density and balance function in senile osteoporosis patients.Methods A prospective casecontrol study was conducted on 216 senile osteoporosis patients who met the inclusion criteria.Patients were given oral calcium and active vitamin D for 12 months.The data values of BMD,balance function,falls incidence and bone pain were compared before versus 6 and 12 months after treatment.Results There were significant differences in BMD of lumbar vertebrae and femur neck,static balance function assessed by the single-leg stance timed tests with closed eyes,dynamic balance function assessed by the Star Excursion Balance Test(SEBT) in directions of east,southeast,south and southwest(all P＜0.05).The incidence of falls was decreased 12 months after treatment as compared with pre-treatment(5.6％ vs.12.5％).The bone pain had no significant difference before versus after treatment(P＞0.05).Conclusions Oral calcium and active vitamin D could increase BMD,improve the balance function and decrease the risk of falls in senile osteoporosis patients.However,it has no significant improvement on bone pain within a short period.
