Current status of photodynamic therapy for unresectable hilar cholangiocarcinoma
10.3969/j.issn.1000-8179.2016.16.517
- VernacularTitle:不可切除肝门胆管癌的光动力学治疗现状
- Author:
Zhiyuan LI
;
Xiaoqi LI
;
Peiyuan CUI
- Publication Type:Journal Article
- Keywords:
hilar cholangiocarcinoma;
photodynamic therapy;
photosensitizer;
endoprostheses;
survival
- From:
Chinese Journal of Clinical Oncology
2016;43(16):735-738
- CountryChina
- Language:Chinese
-
Abstract:
Hilar cholangiocarcinoma is a rare biliary malignant tumor derived from the biliary epithelial cell. The primary current treat-ments for hilar cholangiocarcinoma include surgery and chemotherapy, as well as radiation and photodynamic therapies (PDT). A com-plete resection with negative margins is the only treatment with the potential for cure and the only way to maximize survival. Howev-er, over half of the patients in the advanced stage of hilar cholangiocarcinoma lost the chance for surgery. Radiotherapy and chemo-therapy can prolong patient survival;however, these lack reliable data. Most patients who cannot be treated surgically undergo biliary stenting to relieve the biliary obstruction. The PDT is a new method to treat various malignant tumors. Several clinical studies have shown its local tumor ablation capability. Thus, PDT has broad application prospects in the treatment of unresectable hilar cholangio-carcinoma.
