Correlation between Intima-Media Thickness in Carotid Artery and the Extent of Coronary Atherosclerosis.
10.4070/kcj.2003.33.5.401
- Author:
Ki Rack PARK
1
;
Ki Young KIM
;
Sang Mi YOON
;
Jang Ho BAE
;
In Whan SEONG
Author Information
1. Division of Cardiology, Department of Internal Medicine, College of Medicine, Konyang University, Daejeon, Korea. jhbae@kyuh.co.kr
- Publication Type:Original Article
- Keywords:
Carotid arteries;
Coronary atherosclerosis
- MeSH:
Atherosclerosis;
Carotid Arteries*;
Carotid Artery, Common;
Carotid Artery, Internal;
Chest Pain;
Coronary Angiography;
Coronary Artery Disease*;
Coronary Vessels;
Humans;
Hypertension;
Male;
Risk Factors;
Smoke;
Smoking;
Ultrasonography
- From:Korean Circulation Journal
2003;33(5):401-408
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: We performed this study to elucidate whether there were significant correlations 1) between intima-media thickness (IMT) of carotid artery and the extent of coronary atherosclerosis and 2) between carotid IMT and risk factors of atherosclerosis in patients with coronary atherosclerosis. SUBJECTS AND METHODS: All study subjects (n=326, 200 males, 59+/-10 years) had chest pain and underwent coronary angiography. IMT was measured in the far wall of the internal and common carotid arteries and the carotid bulb using high-resolution ultrasound with a 3-11 MHz linear probe. We also evaluated the presence of plaque in the carotid artery. The extent of coronary atherosclerosis was divided into 4 groups (0, 1, 2, and 3) according to the number of coronary arteries narrowed more than 50% of the diameter. RESULTS: In patients with one or more diseased coronary vessels, IMT of the common carotid artery was thicker (0.81+/-0.15 mm vs. 0.91+/-0.28 mm, p<0.05) and plaques were more frequently found (16% vs. 40%, p<0.05). There was also a significant correlation between the extent of coronary artery atherosclerosis and IMT of the common carotid artery (r=0.217, p<0.001) and the internal carotid artery (r=0.177, p<0.01). Multiple regression analysis revealed hypertension and smoking, among the atherosclerosis risk factors, as independent factors in the IMT of the common carotid artery and carotid bulb. CONCLUSION: We concluded that there was a significant correlation between the extent of coronary artery disease and IMT of the carotid artery;and that hypertension and smoking, of all atherosclerosis risk factors, were independent factors in the IMT of the carotid artery.
