Intravitreal Ranibizumab Injection Combined with Complex Trabeculectomy in Treatment of Neovascular Glaucoma
10.3870/j.issn.1004-0781.2016.09.017
- VernacularTitle:玻璃体腔内注射雷珠单抗联合复合式小梁切除治疗新生血管性青光眼?
- Author:
Chaoqiong WU
;
Jing ZHU
;
Qi ZHANG
- Publication Type:Journal Article
- Keywords:
Ranibizumab;
Glaucoma,neovascular;
Intravitreal injection;
Complex trabeculectomy
- From:
Herald of Medicine
2016;35(9):975-977
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of intravitreal ranibizumab injection combined with complex trabeculectomy in treatment of neovascular glaucoma. Methods Totally 38 patients(38 eyes) of neovascular glaucoma were divided into two groups of 19 cases in each randomly. Patients in treatment group were treateded with complex trabeculectomy after intravitreal injection 0. 05 mL ( 0.5 mg ) ranibizumab 4 - 7 days. Patients in control group were treateded with cyclocryotherapy. Visual acuity, intraocular pressure, iris neovascularization and complications were observed. Results The average intraocular pressure of preoperation and postoperation 1 month in treatment group were (6.5±1.7) kPa and (2.1±1.2) kPa.The difference of intraocular pressure before and after operation was significant. The average preoperative and postoperative intraocular pressure in control group were (6.7±1.9) kPa and (2.5±1.2) kPa . The postoprative intraocular pressure of treatment group was lower than that of control group, the difference was statistically significant( P< 0.05). Visual acuity and operative reaction after operation in treatment group were superior to those in control group. Conclusion Intravitreal injection of ranibizumab combined with complex trabeculectomy in treatment of neovascular glaucoma is safe and effective and worth in clinical application.
