MRI features of glioblastoma in children and review of the literature
10.3969/j.issn.1002-1671.2016.08.027
- VernacularTitle:儿童胶质母细胞瘤的 MRI 表现及文献复习
- Author:
Feng LIU
;
Wenwei TANG
;
Fang LIU
;
Xiaohui LI
- Publication Type:Journal Article
- Keywords:
children;
glioblastoma;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2016;32(8):1269-1271
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the imaging features of MRI in children glioblastoma and improve the understanding of this disease.Methods The clinical data and MR features of 5 cases in children with glioblastoma confirmed by surgery and pathology were analyzed retrospectively. Imaging features including location,shape,growth pattern,peritumoral edema and contrast enhancement were assessed.Results 4 cases occurred in the cerebral hemisphere and 1 in cerebellar hemisphere,all of which manifested obvious mass effect with 2 cases across midline.3 cases were round-like,while another 2 cases were irregular in shape.In spite of 1 case without peritumoral edema, 4 cases performed mild to moderate peritumoral edema.Among all patients,one showed cystic mass,2 caese showed cystic-solid mass,and the other 2 cases showed solid mass.Cystic portion presented long T1 and long T2 signal,as well as low signal on FLAIR. Solid part of lesion showed iso-intense on T1 WI and T2 WI,as well as high signal on FLAIR and DWI.After contrast enhancement,cyst wall showed annular enhancement.Ring-shaped or nodular enhancement was seen in solid components of cystic-solid mass.And solid mass showed irregular and lump-like enhancement.Conclusion Glioblastoma in children has certain characteristic MRI appearances. The surgical and pathological results are still required to establish the final diagnosis.
