Progress and ideas of irritable bowel syndrome animal model construction based on combination of disease and syndrome
10.3969/j.issn.1001-1978.2016.09.004
- VernacularTitle:基于病证结合肠易激综合征动物模型构建方法及研究思路
- Author:
Jianwei WANG
;
Qiuyue ZHANG
;
Fenghua XU
;
Hongyu YE
;
Wenjing ZHAO
- Publication Type:Journal Article
- Keywords:
irritable bowel syndrome( IBS);
combination of dis-ease and syndrome;
animal model;
relation between formulae and diseases;
systemic biology;
research idea
- From:
Chinese Pharmacological Bulletin
2016;32(9):1198-1202
- CountryChina
- Language:Chinese
-
Abstract:
Establishment of combination of disease and syndrome animal model is an ideal technology platform in TCM research. Currently, many scholars have prepared matching IBS animal models combined typical animal models with etiology, which em-bodies the advantages of syndrome differentiation and promotes the development of combination disease and syndrome animal model. Even though, there still exists some problems about sub-jective evaluation on syndromes, paying more attention on dis-ease and less on syndromes. Therefore, we should deepen the pathogenesis of diseases and TCM syndromes research on animal model replication and improve the method of construction of combination of disease and syndrome animal model through the biological research of combination of disease and syndrome sys-tem. By this way, the idea of preparation animal models will be more mature and the scientific connotation of TCM will be pres-ented more exactly.
