Progress of the gut microbiota to affect the development and function of the brain
10.3760/cma.j.issn.2095-428X.2016.12.022
- VernacularTitle:肠道微生物影响大脑发育和功能的研究进展
- Author:
Xiufen ZHANG
;
Hong LI
- Publication Type:Journal Article
- Keywords:
Gut microbiota;
Brain development;
Brain function
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(12):956-958
- CountryChina
- Language:Chinese
-
Abstract:
Gut microbiota is essential to human health,playing a major role in the bidirectional communication between the gastrointestinal tract and the central nervous system through the immunological,hormonal,neural and metabolic pathways.The colonization of the gut microbiota is influenced by multiple and diverse factors,such as the perinatal factors,dietary habits,diseases and antibiotics.The infant is the critical period for modifying the gut microbiota,disruptions during this period of microbiota-host interaction have the potential to affect the development and function of the brain.To regulate the homeostasis of the gut microbiota has its profound influences on improving the symptoms of gastrointestinal and behavior disorders.