Effects of Lactobacillus acidophilus tablets combined with infantile diarrhea paste on serum myocardial enzyme and isozyme levels in children with acute diarrhea
10.3969/j.issn.1005-1678.2016.06.53
- VernacularTitle:嗜酸乳杆菌片联合小儿腹泻贴对小儿急性腹泻患儿血清心肌酶、同工酶水平的影响
- Author:
Jinping LI
;
Mingang LEI
- Publication Type:Journal Article
- Keywords:
Lactobacillus acidophilus tablets;
infantile;
diarrhea paste;
acute diarrhea;
myocardial enzymes;
isozymes
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(6):176-178
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of Lactobacillus acidophilus tablets combined with infantile diarrhea paste in the treatment of acute diarrhea in children.Methods Retrospective study of a total of 92 children with acute diarrhea from our hospital were collected and randomly divided into experimental group and control group with 46 cases in each group.Patients in the control group were treated by conventional treatment, patients in the experimental group were treated by Lactobacillus acidophilus tablets combined with infantile diarrhea paste.The serum myocardial enzyme, isozyme, inflammatory factors and the levels of T lymphocyte were determined, and the clinical efficacy before and after treatment was compared.Results The clinical effective rate of the control group ( 82.61%) was lower than the experimental group ( 95.65%) , with statistical significance ( P<0.05 );compared with the control group, after treatment the serum myocardial enzyme and isozyme of the experimental group decreased, after treatment the serum TNF-α, IL -6 and I -10 levels decreased, after treatment the CD3 +, CD4 + and CD4 +/CD8 +levels increased, CD8 + level decreased, with statistical significance ( P<0.05 ) , There was no adverse reactions such as gastrointestinal discomfort and skin irritation happened in two groups of patients.Conclusion Lactobacillus acidophilus tablets combined with infantile diarrhea paste in the treatment of children with acute diarrhea could reduce serum myocardial enzymes and isozyme levels, improve immune ability and the effect is remarkable.
