Therapeutic Observation of Electroacupuncture and Prucalopride Succinate Tablets for Functional Constipation
10.13460/j.issn.1005-0957.2016.08.0926
- VernacularTitle:电针与普芦卡必利治疗功能性便秘疗效观察
- Author:
Zhen MAO
;
Hongxing ZHANG
- Publication Type:Journal Article
- Keywords:
Constipation;
Electroacupuncture;
Cleveland Clinic Score;
Bristol Score
- From:
Shanghai Journal of Acupuncture and Moxibustion
2016;35(8):926-929
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the clinical efficacies of electroacupuncture and Prucalopride succinate tablets in treating functional constipation.MethodForty patients were randomized into two groups, 20 cases in each group. The treatment group was intervened by electroacupuncture, and the control group was byoral administration of Prucalopride succinate tablets. The major symptoms scores, stool shape score, serum substance P (SP), and somotostatin (SS) were observed.ResultAfter treatment, there were no significant inter-group differences in comparing the changes of defecation frequency and difficulty scores (P>0.05), while there were significant inter-group differences in comparing the changes of incomplete bowel evacuation sensation, abdominal pain, and stool shape scores (P<0.05); the serum SP and SS levels were significantly changed after treatment in both groups (P<0.05); the total effective rate was 90.0% in the treatment group versus 85.0% in the control group, and the difference was statistically insignificant (P>0.05).ConclusionElectroacupuncture and Prucalopride succinate tablets can produce equivalent efficacies in treating functional constipation, and have their own advantages in improving the relevant symptoms. Therefore, treatment should be chosen according to the disease condition.