Correlation between serum uric acid level with coronary artery disease and its severity
10.3969/j.issn.1673-4130.2016.15.005
- VernacularTitle:血尿酸与冠心病及其严重程度相关性研究
- Author:
Li HUA
- Publication Type:Journal Article
- Keywords:
coronary heart disease;
serum uric acid;
coronary angiography
- From:
International Journal of Laboratory Medicine
2016;37(15):2061-2064
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the serum uric acid (SUA) level with the coronary heart disease (CHD) occurrence and severity ,and the differences among different sexes and ages of population .Methods The research subjects were divided into the CHD group(396 cases) and non‐CHD group(792 cases) according to the coronary angiography results .The patients were sub‐divided into the group 1―4 by quartile according to the SUA level .The difference of CHD incidence rate among various groups was analyzed ;the lesion vessel number was used to reflect the CHD severity ,the relation between the SUA level with the lesion severity was analyzed ;the Logistic regression analysis was adopted to analyze the risk of SUA level on CHD . Results (1)The SUA level in the CHD group was higher than that in the non‐CHD group .After sex stratification analysis ,only the difference of female group existed ;the age stratification revealed that the SUA level in the CHD group among 30-70 years old population was significantly higher than that in the non‐CHD group ;(2)in overall females and population aged 30-70 years old ,the prevalence of CHD in the fourth group with highest SUA level was significantly higher than that in other groups .Stratified analysis showed the same effects in the total subjects ,females and subjects of 30 -70 years old population ;(3)the SUA level in the total subjects ,female and 30-70 years old population was positively correlated with the coronary artery lesion vessel number ;(4) the Logistic regression analysis showed that the SUA level in the total subjects ,female and 30 -70 years old population was the risk factor of CHD .Conclusion The SUA level is associated with the CHD incidence rate ,and has a positive correlation with the lesion severity of CHD 30-70 years old populations ,SUA has greater predictive value for CHD and its severity in females and popula‐tions aged 30-70 years old .
