A Case of Epithelioid Angiosarcoma of the Scalp.
- Author:
Jin Hyuk RHO
1
;
Byung Jin LEE
;
Ok Ja JOH
;
See Ryong PARK
Author Information
1. Department of Dermatology, Seoul Veterans Hospital, Korea. rho7@medigate.net
- Publication Type:Case Report
- Keywords:
Epithelioid angiosarcoma;
Scalp
- MeSH:
Cytoplasm;
Endothelial Cells;
Eosinophils;
Epithelioid Cells;
Hemangiosarcoma*;
Humans;
Middle Aged;
Scalp*;
Vacuoles
- From:Korean Journal of Dermatology
2003;41(7):971-973
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Angiosarcoma is a rare malignant tumor of endothelial cell origin. Histopathologically, varied differentiation may be observed even within the same tumor. Epithelioid angiosarcoma is one subset of poorly differentiated angiosarcoma which is a rare variant. We report a case of epithelioid angiosarcoma of the scalp in a 59-year-old man. The patient had a painful solitary, 2x3 cm sized, dome-shaped, firm, erythematous to purplish nodule with crust on the vertex of the scalp. Histopathologically, the tumor was chiefly composed of solid sheets of atypical epithelioid cells with prominent eosinophilic cytoplasm, a large vesicular nuclei, and occasional intracytoplasmic vacuoles. Well to moderately differentiated areas with irregular vascular channel-like structures lined by atypical hyperchromatic endothelial cells were also seen in the peripheral areas of the tumor. Immunohistochemically, the tumor cells were positive with CD31 which is sensitive marker of endothelial cell.
