The clinical research of Yiqi-Wenyang-Gujing decoction and conventional western medicine ;treatment on the elderpatients with chronic glomerulonephritis
10.3760/cma.j.issn.1673-4246.2016.08.008
- VernacularTitle:益气温阳固精汤结合西医常规疗法治疗老年原发性慢性肾小球肾炎临床研究
- Author:
Zhiqiang WANG
- Publication Type:Journal Article
- Keywords:
Glomerulonephritis;
Aged;
Yiqi-Wenyang-Gujing decoction;
Integrated Chinese traditional and western medicine therapy;
Albuminuria;
Glomerular filtration rate
- From:
International Journal of Traditional Chinese Medicine
2016;38(8):697-700
- CountryChina
- Language:Chinese
-
Abstract:
Objective To estimate the effect of Yiqi-Wenyang-Gujing decoction combined with the conventional western therapy on the elderly with chronic glomerulonephritis. Methods The 65 patients who conforming to the diagnostic criteria were randomly divided into the treatment group (33 patients) and control group (32 patients) according to the random number table. The control group was treated with the conventional western therapy, and the treatment group was treated with Yiqi-Wenyang-Gujing decoction based on the former treatment. After the treatment of 8 weeks, the curative effect of edema and the 24 hours urine protein and the changes of renal function were observed. Results Compare with the control group, the 24 hours urinary protein (0.8 ± 0.1 g vs. 1.3 ± 0.7 g, t=4.625), the SCr (132.0 ± 8.5μmol/L vs. 163.9 ± 6.2μmol/L, t=17.242) and the BUN (7.1 ± 2.2 mg/L vs. 9.2 ± 2.5 mg/L, t=3.598) of treatment group significantly decreased (P<0.01);The glomerular filtration rate of treatment group [(73.9 ± 4.2 ml/(min·1.73 m2) vs. 65.4 ± 2.4 ml/(min·1.73 m2), t=9.976] significantly increased (P<0.01). And the degree of edema was relieved more in the treatment group than that of the control group (P=0.049). The total effective rate of the treatment group was significantly better than that (78.8% vs. 46.9%, P=0.016) of the control group. Conclusion The combined Yiqi-Wenyang-Gujing decoction and western medicine treatment on the elderly with chronic glomerulonephritis could improve the kidney function and relieve edema.
