New immunotherapy strategies in breast cancer
10.3969/j.issn.1001-1978.2016.08.001
- VernacularTitle:乳腺癌免疫治疗新策略
- Author:
Linyu YU
;
Mupeng LI
;
Dabin KUANG
;
Congmin ZHANG
;
Xiaoping CHEN
- Publication Type:Journal Article
- Keywords:
breast cancer;
immunotherapy;
cancer vaccines;
bispecific antibodies;
immune checkpoint blockade;
co-stimula-tor;
cytokine therapy
- From:
Chinese Pharmacological Bulletin
2016;32(8):1037-1040
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is the principal cause of death in malig-nancy women , usually treated with the combination of surgery , chemotherapy , radiotherapy and endocrinotherapy .With the de-velopment of cell biology , molecular biology , immunology, im-munotherapy becomes a new field of breast cancer treatment .In this review, we discuss new findings in breast cancer immuno-therapy , including recent successes with bispecific antibodies and immune checkpoint blockade .We also discuss therapeutic cancer vaccines and highlight several additional immunotherapy modalities in early stages of development .