Transmission of HIV drug resistance in antiretroviral treatment-naive HIV-infected individuals
10.3760/cma.j.issn.0254-5101.2016.07.012
- VernacularTitle:未治疗艾滋病患者中HIV耐药株的传播研究
- Author:
Yang LI
;
Hui XING
- Publication Type:Journal Article
- Keywords:
HIV;
Drug resistance;
Transmission;
Associated factors
- From:
Chinese Journal of Microbiology and Immunology
2016;36(7):540-544
- CountryChina
- Language:Chinese
-
Abstract:
Human immunodeficiency virus ( HIV) is commonly transmitted through blood transfu-sion, sexual contact and mother-to-child transmission. The number of patients with HIV infection has kept growing in the last three decades. Although the wide application of antiretroviral therapy ( ART) has effec-tively suppressed the replication of HIV, the emergence of drug resistant mutants compromises the efficacy of ART. What is worse is that there has been transmission of drug resistance strains in ART-na?ve HIV-infected individuals. This review describes the distribution of transmitted drug resistance strains in different regions and high risk population as well as the factors associated with the transmission in recent years.
