Histopathologic responses of human dental pulp to calcium hydroxide and mineral trioxide aggregate as pulp capping agents

VernacularTitle:2种盖髓剂体内直接盖髓后的组织病理学变化
Author: Jing WEN ; Xichao HONG ; Shide YU ; Wenxiu GAO
Publication Type:Journal Article
Keywords: Mineral trioxide aggregate(MTA); Calcium hydroxide(CH); Direct pulp capping; Reparative dentin
From: The Journal of Practical Medicine 2016;32(13):2175-2177
CountryChina
Language:Chinese
Abstract: Objective To investigate human pulpal response to mineral trioxide aggregate (MTA) and calcium hydroxide (CH) as pulp capping agents. Methods This study was conducted on 90 intact first and second premolars of human maxillary and mandibular teeth of 30 volunteers. The patients were randomly assigned into three groups with 10 in each group. Under local anesthesia, the teeth were exposed and capped either with MTA, or CH. After 30, 60, and 90 days, 10 teeth of each group were extracted and prepared for histologic ob-servation. The data were analyzed with Wilcoxon rank sum test and paired t-tests (α = 0.05). Results MTA had a higher success rate and resulted in less pulpal inflammatory response and more predictable hard dentin bridge formation than CH (P < 0.05). Conclusion MTA appears to be a suitable replacement for CH in direct pulp capping.