Risk factors and etiology of multiple drug-resistant bacterial infection of stroke-associated pneumonia pa-tients in intensive care unit
10.3969/j.issn.1006-5725.2016.13.029
- VernacularTitle:重症监护病房脑卒中相关性肺炎多重耐药菌感染的危险因素及病原学分析
- Author:
Deliang WEN
;
Zhibo LI
;
Yichao WEN
;
Weijiang LIU
;
Xuming XIONG
- Publication Type:Journal Article
- Keywords:
Intensive care unit;
Stroke associated pneumonia;
Multiple drug-resistant;
Risk fac-tors;
Etiology
- From:
The Journal of Practical Medicine
2016;32(13):2178-2181
- CountryChina
- Language:Chinese
-
Abstract:
Ojective To determine the risk factors and the clinical distribution of multiple drug resistant bacteria in stroke- associated pneumonia (SAP) patients with multiple drug-resistant bacterial infections from in-tensive care unit, providing guidance for clinical treatment of SAP. Methods A retrospective study was de-signed to analyze the clinical data of the SAP patients from January 2012 to December 2015. Univariate analysis and multivariable regression analysis were taken for risk factors of MDR infections , and investigated the distribu-tion and drug resistance of MDR. Results There were 183 SAP patients, of which 131patients (71.6%) had MDR infection. There are 193 MDR strains in the 131 patients , the first 5 MDR strains were Acinetobacter bau-mannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus and Escherichia coli. MDR in-fection is highly associated with sever unconsciousness , time of stay in ICU longer than 7 days , ventilator time longer than 7 days and late-onset pneumonia and the difference was significant (P < 0.05). Conclusion SAP patients with MDR bacterial infections are in association with the following risk factors: sever unconsciousness , time of stay in ICU longer than 7 days, ventilator time longer than 7 days and late-onset pneumonia. The rate of MDR bacterial infections was high , and these MDR strains were widely different degrees of resistance to many antibiotics.
