Clinical diagnosis and treatment of inflammatory granuloma in central nervous system

VernacularTitle:中枢神经系统炎性肉芽肿8例临床诊治分析
Author: Jianzhong GUO ; Yao WEI ; Hongming JI ; Gangli ZHANG ; Rulei GU
Publication Type:Journal Article
Keywords: Central nervous system disease; Granuloma
From: Chinese Journal of Primary Medicine and Pharmacy 2016;23(17):2617-2620
CountryChina
Language:Chinese
Abstract: Objective To discuss the diagnosis and treatment of inflammatory granuloma in central nervous system(CNS)to provide reference for clinic.Methods Retrospective data included 8 patients with CNS inflammatory granuloma in Department of Neurosurgery,Shanxi People's Hospital,2012 -2015.We analyzed the imaging features, postoperative symptoms,blood and cerebrospinal fluid changes and prognosis.Results 8 cases all received surgical treatment.All the symptoms were improved,and the CT showed that the lesions were disappeared.All the patients had recovered to normal life and work.Conclusion The diagnosis of CNS inflammatory granuloma is difficult.Clinical manifestations are lack of specificity.The blood and cerebrospinal fluid laboratory examination have no abnormal changes.CT and MRI are the main diagnostic methods.Postoperative pathology is the gold standard for diagnosis.The large lesion,frequent episodes of epilepsy,severe neurological deficits and possibility of brain tumor all should be treated by surgery.