Progress in genetic basis of congenital heart disease
10.3760/cma.j.issn.2095-428X.2016.13.003
- VernacularTitle:先天性心脏病遗传学基础研究进展
- Author:
Lian ZHANG
- Publication Type:Journal Article
- Keywords:
Congenital heart disease;
Genetics;
Genetic testing technology
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(13):969-972
- CountryChina
- Language:Chinese
-
Abstract:
Congenital heart disease (CHD)is the most common human congenital malformation,which is the biggest cause of infant morbidity and mortality.Even though it can be corrected by surgical operation,the patient also faces a variety of surgical complications and even the risk of disease recurrence,which brings huge economic pressure to the society.At present,the occurrence of CHD is related to the gene mutation,chromosome variation,environmental fac-tors and epigenetic inheritance.This paper focuses on the genetic basis of CHD and genetic testing technology,to deepen the understanding of the genetic basis of the disease,to provide the basis for the prevention of disease and early diagnosis.
