Interaction between P2X3 and TRPV1 in the mechanism of pain

VernacularTitle:P2 X3与 TRPV1在疼痛机制中的相互作用
Author: Jie YU ; Junying DU ; Jianqiao FANG
Publication Type:Journal Article
Keywords: Pain; P2X3; Transient receptor potential channel vanilloid type 1; Interaction
From: Journal of Medical Postgraduates 2016;29(8):868-871
CountryChina
Language:Chinese
Abstract: Pain, as one of the most common clinical symptoms, seriously affects the quality of life of patients.Transient Re-ceptor Potential Vanilloid Type 1 (TRPV1) and Purinergic receptor(P2X3)are both involved in the transmission of a variety of patho-logical pain signals.Their interaction is less reported.This article reviews the interaction between TRPV1 and P2X3 in the pain signal transduction, and provides a new way for the treatment of pain.