The research progress in endoplasmic reticulum stress with the correlation of osteoporosis
10.16571/j.cnki.1008-8199.2016.08.021
- VernacularTitle:内质网应激通路与骨质疏松相关性的研究进展
- Author:
Minjie RUI
;
Suyang ZHEN
;
Yang GUO
;
Yong MA
- Publication Type:Journal Article
- Keywords:
Endoplasmic reticulum stress;
Osteoporosis;
Pancreatic beta cells;
Osteoblasts;
Osteoclasts;
Mesenchymal stem cells
- From:
Journal of Medical Postgraduates
2016;29(8):877-882
- CountryChina
- Language:Chinese
-
Abstract:
ERS is a kind of universal existence in various cellular stress response.Recently, the research shows that ERS may affect bone metabolism balance from different ways.However, the specific mechanism is still not clear.The relationship between ERS and osteoporosis needs further research.This article will firstly introduce the pathways of ERS, then the relationship between the ERS and osteoporosis will be discussed from pancreatic beta cells, osteoblasts, osteoclasts and mesenchymal stem cells.Lastly, I will give perspectives on the future research on treatment of osteoporosis drug.
