Review on long non-coding RNA DANCR enhances chondrogenic differentiation and proliferation of human synovium-derived mesenchymal stem cell

VernacularTitle:长链非编码 RNA DANCR 促滑膜间充质干细胞向软骨细胞分化作用的研究进展
Author: Chao YANG ; Lei ZHANG ; Liwu ZHOU ; Jianning ZHAO
Publication Type:Journal Article
Keywords: Long non-coding RNA; DANCR; Synovium-derived mesenchymal stem cells
From: Journal of Medical Postgraduates 2016;29(8):892-896
CountryChina
Language:Chinese
Abstract: Long non-coding RNA( LncRNA) is an RNA molecule that is longer than 200 nucleotides and is not translated into a protein.LncRNA DANCR has been identified in hepatocellular carcinoma ( HCC) and markedly increased stemness features of HCC cells to promote tumorigenesis.Recent studies show that DANCR contributes to the differentiation and proliferation of synovium-derived mesenchymal stem cell ( SMSCs) and may be as a key point for this process.This article reviews the role of long non-coding RNA DANCR in enhancing chondrogenic differentiation and proliferation of human SMSCs.