Relevant factors of pulmonary arterial smooth muscle cells proliferation and pulmonary arterial hypertension
10.3760/cma.j.issn.2095-428X.2016.13.018
- VernacularTitle:肺动脉平滑肌细胞增殖相关因子与肺动脉高压
- Author:
Feng ZHANG
;
Yusheng PANG
;
Jinquan LAO
- Publication Type:Journal Article
- Keywords:
Pulmonary arterial smooth muscle cell;
Cell proliferation;
Relevant factor;
Pulmonary arterial hy-pertension
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(13):1031-1033
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary arterial hypertension (PAH)is a disease of unknown etiology that leads to a progressive increase in pulmonary vascular resistance (PVR),if untreated,ultimately right heart failure and high mortality.It is concerted pulmonary vascular contraction and vascular remodeling are the 2 main courses of physiology and pathology leading to PAH,especially the significant role of proliferation of pulmonary arterial smooth muscle cells.A lot of relevant factors are revealed to take a participation into regulating the proliferation of pulmonary arterial smooth muscle cells and finally PAH.
