Research progress of gene mutations associated with myelodysplastic syndromes
10.3760/cma.j.issn.1009-9921.2016.07.020
- VernacularTitle:骨髓增生异常综合征相关基因突变的研究进展
- Author:
Yubing JIAO
;
Yanjuan LIN
- Publication Type:Journal Article
- Keywords:
Myelodysplastic syndromes;
Molecular biology;
Genes mutation;
Prognosis
- From:
Journal of Leukemia & Lymphoma
2016;25(7):445-448
- CountryChina
- Language:Chinese
-
Abstract:
Myelodysplastic syndromes (MDS) is a group of malignant clonal hematopoietic stem cell disorders. With the application of molecular biology techniques in a wide range of scientific research and clinical practice, studies have shown that gene mutation is one of the key factors in the occurrence and progression of MDS. Great clinical heterogeneity of MDS is associated with diversity of genes mutation, and genes research will play an increasingly important role in the diagnosis, classification and prognosis of MDS. In this review, the recent advances on these common genes will be summarized.
