Influence of budesonide intermittent suction to wheezing recurrent,the body height and weight of infants
10.3760/cma.j.issn.1008-6706.2016.17.026
- VernacularTitle:布地奈德间歇雾化吸入治疗对婴幼儿喘息复发及身高、体质量的影响
- Author:
Lifeng WEI
;
Jinghua LI
;
Fengwei CHU
- Publication Type:Journal Article
- Keywords:
Wheezing;
Budesonide;
Infants;
Relapse;
Growth
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(17):2659-2662
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of intermittently inhaled budesonide on wheezing improvement and recurrent in infants,assess their body height and weight development status.Methods 138 wheezing infants were selected.They were randomly divided into the treatment group and the control group,69 children in each group.The treatment group received budesonide therapy when upper respiratory infection symptoms infection,the control group was given ribavirin injection spray treatment.After two weeks treatment,the number of severe wheezing and systemic corticosteroids were observed,the asthma relapse frequency in one year and height and weight were assessed.Results The severe wheezing number and the application of systemic corticosteroids number of the treatment were 1 case (1.50%)and three cases (4.35%),which were lower than the control group 8 cases (11.59%)and 11 cases (15.94%).The difference was statistically significant (χ2 =8.71,P <0.05).The frequency of wheezing within one year of the treatment group was (2.39 ±0.41)times,which was lower than (4.56 ±0.45)times of the control group, the difference was statistically significant (t =9.06,P <0.05).Comparison of height and weight of the two groups after one year,the differences was not statistically significant (t =1.45,1.18,all P >0.05).Conclusion Budesonide in the treatment of intermittent wheezing infants can significantly improve the wheezing and reduce the use of systemic corticosteroids,reduce the relapse rate.It has no effect on the growth and development of infants.
