Preventive effect of statins for hepatocellular carcinoma
10.3760/cma.j.issn.1006-9801.2016.07.020
- VernacularTitle:他汀类药物对肝细胞癌的预防作用
- Author:
Tao ZHENG
;
Jiamei YANG
- Publication Type:Journal Article
- Keywords:
Carcinoma,hepatocyte;
Statins;
Prevention
- From:
Cancer Research and Clinic
2016;28(7):501-504
- CountryChina
- Language:Chinese
-
Abstract:
Statins, hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors , are widely used as a class of lipid-lowering drugs in clinic. Recent studies have shown that the use of statins can be anti-inflammatory, anti-fibrosis and reduce the incidence of hepatocellular carcinoma (HCC), which may provide a new method for the preventive treatment of HCC. This article will review the current research progress of statins, including the clinical evidence, the molecular mechanisms of anti-inflammatory, anti-fibrosis and anti-tumor in liver.
