Perspective on B-cell lymphoma treatment
10.3969/j.issn.1000-8179.2016.14.496
- VernacularTitle:B细胞淋巴瘤之治疗展望
- Author:
Muchen ZHANG
;
Weili ZHAO
- Publication Type:Journal Article
- Keywords:
B-cel lymphoma;
monoclonal antibody;
targeted therapy;
stem cel transplantation;
cel ular immunotherapy;
radioimmunotherapy
- From:
Chinese Journal of Clinical Oncology
2016;43(14):607-612
- CountryChina
- Language:Chinese
-
Abstract:
B-cell lymphoma is a heterogeneous group of disorders involving malignant proliferation of B lymphocytes, accounting for approximately 85%of non-Hodgkin lymphoma. Combined use of rituximab and chemotherapy remarkably improves the survival of pa-tients with B-cell lymphoma. Despite the increase in treatment response, some patients suffer relapsed or refractory lymphoma. Nu-merous novel treatment options have been developed in pre-clinical and clinical practice, including targeted therapies, auto-hemato-poietic stem cell transplantation, cellular immunotherapy, and radioimmunotherapy. This review describes recent advances in B-cell lymphoma treatment and discusses future perspectives.
