Research on the effect of two kinds of antibiotic therapeutic combined with humanistic care for neonates with infectious pneumonia and for intestinal micro ecology
10.3760/cma.j.issn.1008-6706.2016.16.016
- VernacularTitle:青霉素、头孢菌素结合人性化护理治疗新生儿肺炎及对肠道微生态影响研究
- Author:
Lina ZHENG
- Publication Type:Journal Article
- Keywords:
Pneumonia;
Anti -bacterial agents;
Nursing;
Enterobacteriaceae
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(16):2461-2464
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of two kinds of antibiotic therapeutic combined with humanistic care for neonates with infectious pneumonia and for intestinal micro ecology.Methods 210 neonates with infectious pneumonia and without complications from March 2011 to July 2013 were randomly divided into the cephalosporins group(n =50),the penicillins group(n =48)and the combination group(n =52),60 healthy neonates were selected as control.The cure rate,cure time in these groups were compared and the intestinal micro flora were calculated after 5 days with antibiotic treatment to evaluate the antibiotic effect to neonatal intestinal micro ecology.Results There was no significant difference between the cure rate of the cephalosporins group (76.00%),penicillins group (70.83%)and combination group(71.15%)(χ2 =2.517,P >0.05).The bifidobacteria quantity in the drug groups was significantly lower than that in the control group(t =4.600,3.634,4.275,all P <0.01),while the quantity of enteric bacilli(t =4.600,3.634,4.275,all P <0.01),enterococci(t =5.295,4.873,5.041,all P <0.01)and pep-tostreptococcus (t =3.056,2.900,3.113,all P <0.01 )in the drug groups were higher than those in the control group,but the quantity of bacteroidosis had no significant difference among the three groups (t =0.112,1.096, 1.943,all P >0.05).Conclusion Cephalosporin antibiotics and combination is not superior to penicillin,but in-clined to combined medication;antibiotics will destroy the neonatal intestinal micro ecological imbalance,endanger the health of newborn.
