Expression levels and targets of more than fifty miRNAs in glioma
10.3969.j.issn.1671-7856.2016.07.014
- VernacularTitle:50余种miRNA在神经胶质瘤中的表达水平及作用靶点
- Author:
Taiqi LIU
;
Siyu CHEN
;
Wende LI
;
Ren HUANG
- Publication Type:Journal Article
- Keywords:
Glioma;
miRNA;
Target
- From:
Chinese Journal of Comparative Medicine
2016;26(7):79-84
- CountryChina
- Language:Chinese
-
Abstract:
miRNAs are a class of small endogenous RNAs that degrade target mRNAs or repress their translation process. Several miRNAs in glioma are up?regulated, while some others down?regulated. Some miRNAs promote tumorigenesis; some others, however, play a similar function of tumor suppressor genes. Therefore, studies on the expression profiles of miRNAs in glioma may afford auxiliary basis for early clinical diagnosis and novel srtategies for therapy of glioma. This paper will review on researches about the expression levels of miRNAs and their targets in glioma.
