The adiponectin level in gingival crevicular fluid in patients of chronic periodontitis with diabetes mellitus type 2

VernacularTitle:慢性牙周炎伴2型糖尿病患者龈沟液中脂联素水平的检测及意义
Author: Daozhou LIU ; Wanhong WU ; Hui JIANG ; Fan ZHANG ; Ping HUANG
Publication Type:Journal Article
Keywords: Chronic periodontitis(CP); Diabetes mellitus(DM); Gingival crevicular fluid(GCF); Adiponectin
From: Journal of Practical Stomatology 2016;32(4):565-568
CountryChina
Language:Chinese
Abstract: Objective:To examine the adiponectin level in gingival crevicular fluid(GCF)in patients of chronic periodontitis with dia-betes mellitus type 2.Methods:20 patients of diabetes mellitus type 2 with chronic periodontitis(DM&CP),20 of periodontitis(CP) and 20 health subjects(H)were included.The periodontal indexes (SBI,PLI,PD and AL)were measured,GCF samples were quan-tified by periotron 8000,the adiponectin content in GCF was tested by adiponectin ELISA kit.The relationship between the adiponectin level in GCF and the periodontal indexes of the DM&CP patients was analyzed statistically.Results:The adiponectin level in GCF in group DM&CP was significantly lower than that in the other 2 groups(P <0.05).The adiponectin levels in GCF in group CP and H were not statistically different.The adiponectin level in GCF was negatively correlated with PD and AL(P <0.05),but had no correlation with SBI and PLI(P >0.05).Conclusion:Decrease of adiponectin in GCF may play a role in the development of DM&CP.