Anti-fatigue activity of fermented grain-containing blueberry anthocyanins
10.7644/j.issn.1674-9960.2016.07.006
- VernacularTitle:含蓝莓花色苷的谷物发酵物抗疲劳作用研究
- Author:
Ziyu WANG
;
Jingming FU
;
Soudan SUN
;
Wei LIU
;
Wei PANG
;
Lingjia QIAN
;
Yugang JIANG
- Publication Type:Journal Article
- Keywords:
fermented grain-containing blueberry anthocyanins;
anti-fatigue;
mice
- From:
Military Medical Sciences
2016;40(7):558-560
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the anti-fatigue activity of fermented grain-containing blueberry anthocyanins ( LANHE,LH) in mice.Methods Experiments were conducted in two phases .In the first phase , forty mice were randomly divided into four groups:control group(distilled water,dw) and three LH administration groups (8.75,17.5 and 35.08 ml/kg body mass).In the second phase, mice were randomly divided into two groups:high-dose LH group (35.08 ml/kg body mass) and control group (dw 35.08 ml/kg body mass).After four weeks, a forced swimming test was performed and the biochemical parameters related to fatigue were examined .Results and Conclusion The administration groups showed a significant increase of swimming time to exhaustion compared with the control group , especially the high-dose group ( P<0.001).There was no significant change in the blood lactate between the two groups , but at 20 min after swimming, the lactic acid(LA) contents of the high-dose group were lower than in the control group (P>0.05).LH could significantly increase the liver glycogen contents and decrease the serum contents (P<0.05).These data indicate that LH has anti-fatigue activity and can elevate the exercise tolerance in mice .
